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Updated: Apr 25, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
Published on: February 8, 2017
An approach to compare bio-ontologies portals
Julien Grosjean1, Lina F Soualmia1, Khedidja Bouarech2
1CISMeF & TIBS, LITIS EA4108, Rouen University Hospital, France.
Comparing the National Center for Biomedical Ontologies (NCBO) BioPortal and CISMeF HeTOP projects reveals functional similarities and potential for merging. Key differences lie in their core purposes and data management strategies.
Area of Science:
- Biomedical Informatics
- Information Science
Background:
- Biomedical information retrieval relies heavily on terminologies and ontologies (T/O).
- The proliferation of diverse T/O presents challenges for concept identification.
- NCBO BioPortal and CISMeF HeTOP were developed to address these challenges.
Purpose of the Study:
- To compare the NCBO BioPortal and CISMeF HeTOP projects.
- To establish criteria for evaluating bio-ontologies portals.
Main Methods:
- Development of a comparative framework based on goals, features, technologies, and usability.
- Application of these criteria to evaluate BioPortal and HeTOP.
Main Results:
- Both BioPortal and HeTOP facilitate T/O access and sharing.
- Significant differences exist between the portals due to their distinct primary objectives.
- Shared basic functionalities were identified.
Conclusions:
- A functional merge between BioPortal and HeTOP is feasible.
- Challenges for integration include data repository consolidation and policy alignment for T/O content.
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