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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

897
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
897
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

24
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...
24
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

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Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
21
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
556
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

30
The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
30
Cells and Secretions of the Pancreas01:16

Cells and Secretions of the Pancreas

12.5K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
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Related Experiment Video

Updated: Apr 24, 2026

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
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Pancreatic cystic neoplasms.

Faten Limaiem1, Tahar Khalfallah2, Leila Ben Farhat3

  • 1Department of Pathology, Mongi Slim Hospital, Université de Tunis El Manar, Faculté de Médecine de Tunis, La Marsa, Tunisia.

North American Journal of Medical Sciences
|September 12, 2014
PubMed
Summary

This study reviewed 10 pancreatic cystic neoplasms, finding mucinous cystadenoma most common. Understanding these rare tumors is key for accurate diagnosis and patient management.

Keywords:
ImmunohistochemistryMucinous cystic neoplasmsPancreasSerous cystic neoplasmsSolid pseudopapillary neoplasm

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Area of Science:

  • Gastroenterology
  • Surgical Pathology
  • Oncology

Background:

  • Pancreatic cystic neoplasms are rare, accounting for about 0.5% of all pancreatic tumors.
  • This study focuses on the clinicopathological features of these uncommon lesions.

Purpose of the Study:

  • To describe the clinicopathological characteristics of pancreatic cystic tumors.
  • To aid clinicians in accurate diagnosis and optimal patient management.

Main Methods:

  • Retrospective review of 10 pancreatic cystic neoplasm cases diagnosed between 2000-2013.
  • Utilized the 2010 World Health Organization (WHO) classification for tumor grouping.
  • Analysis included patient demographics, clinical presentation, imaging findings, and histopathological examination.

Main Results:

  • The study included 9 female and 1 male patient (mean age 37.5 years).
  • Common symptoms were epigastric/abdominal pain and vomiting. CT scans revealed cystic lesions ranging from 2-10 cm.
  • Diagnoses included mucinous cystadenoma (4), serous cystic neoplasm (2), solid pseudopapillary neoplasm (2), mucinous cystadenocarcinoma (1), and intraductal papillary mucinous neoplasm with invasive carcinoma (1).

Conclusions:

  • Accurate diagnosis and effective management of pancreatic cystic neoplasms require a thorough understanding of their diverse clinicopathological features.
  • This knowledge is crucial for guiding clinical decisions and improving patient outcomes.