Related Experiment Video
Updated: Apr 24, 2026

08:01
A Web Tool for Generating High Quality Machine-readable Biological Pathways
Published on: February 8, 2017
21.2K
Integrated interactive chart as a tool for teaching metabolic pathways
Stavros Kalogiannis1, Ioannis Pagkalos, Panagiotis Koufoudakis
1TEI of Thessaloniki, Department of Nutrition and Dietetics, Thessaloniki, Greece.
Summary
An interactive energy metabolism chart aids biochemistry education by visualizing metabolic pathways. Students found this tool helpful for understanding complex interconnections and enhancing their learning experience.
Area of Science:
- Biochemistry
- Educational Technology
Background:
- Existing metabolic maps lack interactive and integrated visualization capabilities.
- Understanding complex energy metabolism pathways (glucose, fatty acids, amino acids) is crucial in biochemistry.
Purpose of the Study:
- To present an interactive chart of energy metabolism with didactic functions.
- To complement existing metabolic maps with enhanced visualization and navigation.
Main Methods:
- Developed an interactive chart illustrating catabolic and biosynthetic pathways.
- Integrated information sheets with chemical structures, KEGG links, and reaction navigation.
- Designed for intuitive user navigation across metabolic pathways.
Main Results:
- The interactive chart visualizes major metabolic pathways of glucose, fatty acids, and amino acids.
- Users can access detailed information on metabolites and reactions, including structural formulae and external database links.
- Navigation features allow users to follow metabolic flows and observe transformations, enhancing comprehension.
Conclusions:
- The interactive chart serves as a valuable teaching aid for biochemistry.
- Students reported improved understanding of metabolic pathways and their interconnections.
- The tool is perceived as user-friendly, enjoyable, and desirable for classroom use.
Related Concept Videos
Overview of Metabolism
25.6K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
25.6K
Introduction to Metabolism
3.1K
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
3.1K
Respiration Pathways
897
Cellular respiration is a fundamental metabolic process that enables organisms to generate energy from organic molecules. One of its central pathways is the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle, which plays a crucial role in energy production and biosynthetic processes.Conversion of Pyruvate to Acetyl-CoAThe pyruvate generated from glycolysis undergoes oxidative decarboxylation by the pyruvate dehydrogenase complex, producing acetyl-CoA, one molecule of NADH, and one...
897
Overview of Protein Metabolism
4.4K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
4.4K
Overview of Fatty Acid Metabolism
25.3K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
25.3K
Cellular Respiration
3.0K
Cellular respiration is a crucial metabolic process through which cells obtain energy from organic substances, mainly glucose, to produce adenosine triphosphate (ATP). This process includes the oxidation of substrates and the transfer of electrons to a separate electron acceptor, facilitating ATP synthesis through a sequence of biochemical reactions.Glycolysis: The Initial StepGlycolysis is the first stage of cellular respiration, occurring in the cytoplasm of both prokaryotic and eukaryotic...
3.0K

