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Updated: Apr 23, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Principles of surgical treatment of malignant melanoma
Charles W Kimbrough1, Kelly M McMasters1, Eric G Davis1
1The Hiram C. Polk, Jr. Department of Surgery, University of Louisville School of Medicine, 550 South Jackson Street, Louisville, KY 40202, USA.
Abstract:
Although melanoma represents less than 5% of all skin cancers, it is responsible for the bulk of skin cancer-related deaths. Nevertheless, despite this aggressive reputation, most patients with cutaneous melanoma will be surgically cured of their disease. Early detection allows for curative resection, and 5-year survival for all stages of melanoma is 91%. This review outlines the surgical treatment of melanoma, including principles of wide local excision and management of the regional lymph nodes.

