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Updated: Apr 23, 2026

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
Radiation safety consideration during intraoperative radiation therapy
Paul N Mobit1, Priyadarshini Rajaguru2, Michael Brewer2
1Department of Radiation Oncology, University of Mississippi Medical Center, 350 West Woodrow Wilson Drive, Suite 1600, Jackson, MS 39213, USA mobit_paul@yahoo.ca.
This study assessed radiation exposure from the Axxent Electronic Brachytherapy System during intraoperative radiation therapy (IORT). Movable lead shields significantly reduce exposure, allowing safe use in standard operating rooms with protective gear.
Area of Science:
- Medical Physics
- Radiation Oncology
Background:
- Intraoperative radiation therapy (IORT) systems require careful radiation safety assessments.
- The Axxent Electronic Brachytherapy System is a novel IORT device necessitating evaluation of its radiation output.
Purpose of the Study:
- To measure radiation exposure rates around the Axxent Electronic Brachytherapy System during phantom and clinical treatments.
- To determine the effectiveness of lead shielding in reducing radiation exposure.
- To assess the feasibility of using the system in standard operating rooms.
Main Methods:
- Utilized in-house-designed phantoms for initial radiation exposure measurements.
- Conducted radiation surveys during clinical IORT procedures on breast, floor of the mouth, and neck cancer patients.
- Measured exposure rates at various distances and assessed the impact of movable lead shields.
Main Results:
- Exposure rates of 200 mR/h at 30 cm were recorded during IORT with surface applicators and balloons.
- Movable lead shields reduced radiation exposure rates by over 95%.
- The 50-kVp X-ray source allows IORT in regular operating rooms with appropriate shielding and personal protective equipment.
Conclusions:
- The Axxent Electronic Brachytherapy System can be safely operated in standard operating rooms.
- Movable lead shields are highly effective in mitigating radiation exposure.
- Adherence to safety protocols, including lead aprons and shields, is crucial for personnel protection during IORT.
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