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Updated: Apr 22, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Role of mitral valve repair in infective endocarditis
Background And Aim Of The Study:
Mitral valve reconstruction (MVP) is currently the standard treatment for degenerative mitral regurgitation (MR). However, when MR is due to infective endocarditis (IE) the range of pathophysiology present often makes any repair challenging. Hence, the authors' clinical experience of MVP to treat MR caused by IE was analyzed.
Methods:
Between September 2004 and March 2011, a total of 26 patients (20 males, six females) who had been diagnosed with MR due to IE (single surgeon, retrospective review) were operated on. Among the 26 patients (17 active, nine healed; six Carpentier type I, 20 Carpentier type II), MVP was performed in 11 patients (42.3%), of which six were active cases and five were healed. All MVP procedures included ring annuloplasty. A variety of repair techniques was used, including triangular resection (n = 3), pericardial patch reconstruction (n = 4), commissuroplasty (n = 4), artificial chordoplasty (n = 1), chordae transfer (n = 2), and secondary chordae resection (n = 1). Six of 17 patients who had a pathology favorable for repair underwent valve replacement; the etiologies were underlying valvular disease (n = 2, rheumatic pathology), Child's group C liver cirrhosis (n = 1), second redo sternotomy (n = 1), multivalvular disease (n = 1), and critical medical condition (n = 1, septic shock).
Results:
The mean follow up duration was 35.7 months (range: 0.1-84.9 months). Among the repair group, none of the patients showed residual MR on postoperative echocardiography. There were no early or late deaths, and no patient showed newly developed MR during the follow up. Among the replacement group, three patients died of noncardiac causes during the follow up (two early deaths and one late death).
Conclusion:
MVP for MR due to IE showed successful clinical outcomes. Valve replacement was performed in some patients with a repair-favorable pathology, after taking into consideration any comorbidities. Whilst standard repair techniques were sufficient, careful decision-making was the key to achieving excellent results for MVP.
Insights
Mitral valve reconstruction (MVP) for mitral regurgitation (MR) caused by infective endocarditis (IE) demonstrated successful clinical outcomes. Careful patient selection and standard repair techniques are key to achieving excellent results in MVP for IE.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Valvular Heart Disease
Background:
- Degenerative mitral regurgitation (MR) is typically treated with mitral valve reconstruction (MVP).
- Mitral regurgitation due to infective endocarditis (IE) presents unique challenges for repair due to diverse pathophysiology.
- This study analyzes the clinical experience of MVP for MR caused by IE.
Purpose of the Study:
- To evaluate the clinical outcomes of mitral valve reconstruction (MVP) in patients with mitral regurgitation (MR) secondary to infective endocarditis (IE).
- To assess the feasibility and efficacy of various repair techniques in complex IE-related MR cases.
- To determine the factors influencing the decision between valve repair and replacement in this patient population.
Main Methods:
- A retrospective review of 26 patients with MR due to IE who underwent surgery between 2004 and 2011.
- Mitral valve reconstruction (MVP) was performed in 11 patients, utilizing techniques such as ring annuloplasty, triangular resection, and pericardial patch reconstruction.
- Valve replacement was performed in 6 patients due to comorbidities or complex pathology.
Main Results:
- No residual MR was observed postoperatively in the MVP group, with no early or late deaths.
- No new MR developed during a mean follow-up of 35.7 months in the repair group.
- Three non-cardiac deaths occurred in the valve replacement group during follow-up.
Conclusions:
- Mitral valve reconstruction (MVP) is a successful treatment option for MR caused by IE.
- Standard repair techniques are effective, but careful consideration of comorbidities is crucial for decision-making.
- Excellent clinical outcomes can be achieved with judicious patient selection and appropriate surgical strategy.
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