Functional optoacoustic human angiography with handheld video rate three dimensional scanner
Xosé Luís Deán-Ben1, Daniel Razansky1
1Institute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Ingolstädter Landstraβe 1, 85764 Neuherberg, Germany ; Faculty of Medicine, Technical University of Munich, Ismaninger Straβe 22, 81675 Munich, Germany.
Photoacoustics
|October 11, 2014
Summary
A new portable optoacoustic imaging system offers real-time, 3D visualization of deep human tissues. This technology provides high-resolution images for enhanced medical diagnostics and treatment monitoring.
Area of Science:
- Biomedical optics
- Medical imaging technology
- Diagnostic tools
Background:
- Optoacoustic imaging offers high optical contrast and spatial resolution.
- It enables simultaneous imaging of tissue anatomy, function, and molecular contrast in deep tissues.
- Current imaging modalities often lack volumetric data with high temporal resolution.
Purpose of the Study:
- To develop a portable clinical system for real-time, 3D optoacoustic visualization of deep human tissues.
- To demonstrate the system's capability for high-resolution volumetric multispectral optoacoustic tomography (vMSOT).
- To explore its potential for diagnostic and treatment monitoring applications.
Main Methods:
- Development of a portable, clinical-grade optoacoustic imaging system.
- Utilizing volumetric multispectral optoacoustic tomography (vMSOT) for deep tissue imaging.
- Real-time data acquisition and processing for video-rate imaging.
Main Results:
- Successful development of a portable 3D optoacoustic imaging system.
- Demonstrated high-resolution vMSOT imaging of human volunteers' tissues.
- Real-time visualization of tissue morphology and functional parameters like blood oxygenation.
Conclusions:
- The developed system provides powerful performance for deep tissue imaging.
- It offers significant potential for new diagnostic and treatment monitoring value.
- Potential applications include cardiovascular disease, lymphatic disorders, breast lesions, and inflammation.


