Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dependence01:17

Drug Dependence

1.9K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.9K
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

1.6K
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
1.6K
Drugs Acting on Autonomic Ganglia: Stimulants01:23

Drugs Acting on Autonomic Ganglia: Stimulants

2.2K

Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
2.2K
Stimulants01:29

Stimulants

1.3K
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
1.3K
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

976
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
976
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

1.6K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In Memoriam: Maurice A. Mufson, MD, MACP.

The American journal of the medical sciences·2026
Same author

A Rare Case of Metastatic Pulmonary Sarcomatoid Carcinoma.

Cureus·2025
Same author

Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: A Case Report and Clinical Insights.

Cureus·2025
Same author

Cancer of Unknown Primary With Squamous Cell Carcinoma Phenotype Presenting as Isolated Axillary Mass.

Cureus·2025
Same author

Musical Hallucinations in an Elderly Female With Hearing Loss.

Cureus·2024
Same author

Atypical Lyme Disease Rash: A Case Report.

Cureus·2024

Related Experiment Video

Updated: Apr 22, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
09:25

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

10.8K

Update on adolescent tobacco cessation.

Madeline M Keyser, Lynne J Goebel

    The West Virginia Medical Journal
    |October 18, 2014
    PubMed
    Summary

    Adolescent tobacco use is declining in West Virginia, aided by programs like Not on Tobacco (NOT) and RAZE. Further research is essential to enhance adolescent tobacco cessation success rates.

    Area of Science:

    • Public Health
    • Adolescent Health
    • Tobacco Control

    Background:

    • Adolescent tobacco use remains a significant public health concern.
    • West Virginia has implemented specific programs, such as Not on Tobacco (NOT) and RAZE, to address this issue.
    • Understanding the efficacy of current interventions is crucial for improving cessation outcomes.

    Purpose of the Study:

    • To provide an overview of recent research on adolescent tobacco cessation.
    • To identify effective and ineffective strategies for adolescent tobacco cessation.
    • To highlight areas where further research is needed to improve cessation rates.

    Main Methods:

    • Literature review of recent studies on adolescent tobacco cessation.
    • Analysis of program effectiveness, including Not on Tobacco (NOT) and RAZE.

    More Related Videos

    A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
    09:30

    A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

    Published on: January 18, 2018

    8.4K
    Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
    08:39

    Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies

    Published on: August 25, 2018

    29.0K

    Related Experiment Videos

    Last Updated: Apr 22, 2026

    Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
    09:25

    Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

    Published on: January 10, 2015

    10.8K
    A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
    09:30

    A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

    Published on: January 18, 2018

    8.4K
    Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
    08:39

    Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies

    Published on: August 25, 2018

    29.0K
  • Synthesis of findings on successful and unsuccessful cessation approaches.
  • Main Results:

    • Adolescent tobacco use shows a decreasing trend in West Virginia.
    • Specific programs like NOT and RAZE are part of the state's cessation efforts.
    • The review identifies various factors influencing cessation success and failure.

    Conclusions:

    • While trends are positive, continued efforts and research are necessary.
    • Improving adolescent tobacco cessation requires a deeper understanding of effective strategies.
    • Further investigation is needed to optimize interventions and reduce tobacco use among adolescents.