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Updated: Apr 21, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Malignant melanoma with metastatic melanoma to the heart]
Martin Frydland1, Hanne Elming, Ole Ahlehoff
1Istedgade 121, 2. th., 1650 København V. martin.frydland@me.com.
Abstract:
Primary cancer of the heart is rare with an incidence of approximately 0.05%. Secondary tumours are more frequent with an incidence up to 1%. Malignant melanoma (MM) is causing an increasing health concern among young, white, Caucasians with an increasing incidence in Northern Europe of 5:100.000 so far. In autopsy-studies MM have shown a metastasis rate to the heart higher than 50%. We present two case stories with metastatic melanoma to the heart. Physicians addressing patients presenting with cardiac symptoms and a history of MM should be aware of the possibility of cardiac metastasis.
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