Related Experiment Video
Updated: Apr 21, 2026

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
[Gastric carcinoma is the most frequent Epstein-Barr virus-associated malignancy]
1Onkologisk Klinik, Rigshospitalet, Blegdamsvej 9, 2100 København Ø. jeppe.friborg@regionh.dk
Abstract:
Epstein-Barr virus (EBV) is associated with 8% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre-diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.
More Related Videos
Related Concept Videos
Gastritis II: Pathophysiology
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Peptic Ulcer

