Urinary protein biomarker database: a useful tool for biomarker discovery

Area of Science:

• Biomedical Informatics
• Proteomics
• Clinical Chemistry

Background:

• Biomarker databases are crucial for researchers studying protein-disease relationships.
• Existing databases facilitate knowledge acquisition and data reanalysis for biologists and bioinformaticians.

Purpose of the Study:

• To introduce a manually curated database focused on urinary protein biomarkers.
• To consolidate and organize published literature on urinary protein biomarkers.

Main Methods:

• Manual curation of published literature.
• Inclusion of studies reporting urinary protein biomarkers.
• Data organization for cross-study comparison and analysis.

Main Results:

• The database currently contains limited disease-specific biomarker candidates reported by multiple studies.
• This reflects the nascent stage of urinary biomarker discovery.

Conclusions:

• The urinary protein biomarker database serves as a valuable tool for researchers.
• As data accumulates and technology advances, the database will become more comprehensive and impactful.
• It will play a significant role in future biomarker discovery and validation studies.