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Voice prostheses, microbial colonization and biofilm formation
Matthias Leonhard1, Berit Schneider-Stickler
1Department of Otorhinolaryngology and Head and Neck Surgery, Medical University Hospital Vienna, Vienna, Austria.
Advances in Experimental Medicine and Biology
|November 5, 2014
Summary
Total laryngectomy (surgical removal of the voice box) significantly impacts quality of life. Voice prostheses improve voice restoration, but biofilm formation limits device lifespan, causing complications and increased costs.
Area of Science:
- Otolaryngology
- Biomaterials Science
- Microbiology
Background:
- Total laryngectomy for advanced laryngeal and hypopharyngeal cancer leads to diminished quality of life, including voice loss, permanent tracheostoma, and potential dysphagia.
- Voice prostheses are the current standard for voice rehabilitation post-laryngectomy, offering superior and faster voicing outcomes compared to esophageal speech.
- Microbial biofilm formation on voice prostheses is a primary limitation, leading to device dysfunction, leakage, and increased risk of pneumonia.
Purpose of the Study:
- To review the current challenges and advancements in voice prosthesis technology for laryngectomized patients.
- To highlight the impact of biofilm formation on device longevity and patient well-being.
- To explore future technological and scientific approaches to mitigate biofilm-related issues.
Main Methods:
- Literature review of advancements in voice prosthesis design and materials.
- Analysis of scientific insights into biofilm development and material interactions.
- Evaluation of current and emerging technologies for combating microbial colonization.
Main Results:
- Voice prostheses represent a significant improvement in voice rehabilitation after total laryngectomy.
- Polyspecies biofilm formation remains a critical factor limiting the functional lifespan of voice prostheses.
- Despite material and design improvements, microbial colonization continues to cause device failure, patient discomfort, and healthcare expenses.
Conclusions:
- Ongoing research and technological innovation are crucial for improving voice prosthesis performance and patient quality of life.
- Addressing biofilm formation is key to extending device longevity and reducing complications.
- Future strategies may involve novel materials, antimicrobial coatings, or improved prosthesis designs to overcome current limitations.
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