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Updated: Apr 21, 2026
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Confocal (en face) optical coherence tomography in vascularized retinal pigment epithelium detachment
Florence M Coscas1, Gabriel J Coscas, Eric H Souied
1From *Centre Hospitalier Intercommunal de Creteil, Creteil, and †Centre de l'Odeon, Paris, France.
Purpose:
To describe the relationship between pigment epithelial detachment (PED) and choroidal neovascularization (CNV) by overlay of en face optical coherence tomography (OCT) and indocyanine green angiography/scanning laser ophthalmoscopy (SLO).
Methods:
Observational case report of a 75-year-old patient with age-related macular degeneration who presented with reduced vision and a vascularized PED-V scanned with an en face OCT ophthalmoscope.
Results:
The OCT scan demonstrated the actual route of the CNV from the choroid to the subretinal space and a clearly delineated highly reflective area behind the vascularized PED and serous detachment; it also showed hyperreflectivity in the outer retina at the site of the lesion.
Conclusions:
En face OCT allows for better evaluation of intraretinal changes in patients with vascularized PED. In this case, OCT and SLO showed different morphologic changes in active lesions and may be helpful in identifying the site of occult CNV. This may have prognostic and therapeutic significance.
