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Published on: May 26, 2023
Late spectral-domain optical coherence tomography findings in sub-internal limiting membrane hemorrhage
Amanda Rey1, Alfredo Adán, Victor Llorenç
1Department of Ophthalmology, Hospital Clinic de Barcelona, Universidad de Barcelona, Barcelona, Spain.
Purpose:
To report spectral-domain optical coherence tomographic (OCT) findings during the natural history of a sub-internal limiting membrane (sub-ILM) hemorrhage.
Methods:
Observational case report of a 20-year-old man with myeloid acute leukemia who presented a spontaneous resolution of a premacular hemorrhage, which was demonstrated by OCT. During the 12-month follow-up, periodic ophthalmologic and OCT examinations were performed.
Results:
A premacular hemorrhage was revealed in fundus examination, and spectral-domain OCT demonstrated a highly hyperreflective band just above the premacular hemorrhage consistent with the ILM. At 6-month follow-up, the macula was free of blood. The OCT scans after spontaneous resolution of the hemorrhage showed a thickened hyperreflective membrane (ILM) and a prominent hyporeflective premacular cavity. Six months later, this premacular cavity had resolved.
Conclusion:
These late OCT findings in sub-ILM hemorrhage have not been described in spontaneous evolution and confirm the sub-ILM location of a premacular hemorrhage.

