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Updated: Apr 20, 2026
Global Level Quantification of Histone Post-Translational Modifications in a 3D Cell Culture Model of Hepatic Tissue
Published on: May 5, 2022
A trial proteomics fingerprint analysis of HepaRG cells by FD-LC-MS/MS
Katsunori Nakata1, Tomoko Ichibangase, Ryoichi Saitoh
1Laboratory of Proteomics Analysis, Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo-shi, Tokyo 202-8585, Japan. k-imai@musashino-u.ac.jp.
Abstract:
A proteomics profile analysis was performed on a human hepatocyte carcinoma cell line (HepaRG) by using the FD-LC-MS/MS method. One hundred and fifty-eight proteins were newly identified for the first time of which 10 were found to be specific to human hepatocytes. These proteins are a "proteomics fingerprint" that can be used to characterize HepaRG cells.
