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Updated: Apr 20, 2026
Surgical Technique for Superior Cervical Ganglionectomy in a Murine Model
Published on: December 2, 2022
Transoral submandibular ganglion neurectomy: an anatomical feasibility study
Todd Spock1, Henry T Hoffman2, Arjun S Joshi3
1Division of Otolaryngology-Head and Neck Surgery, George Washington University, Washington, DC, USA.
Background:
The management of sialorrhea can be difficult for both the patient and the clinician. Current management includes behavioral modification, anticholinergics, botulinum injections, and a variety of surgical options, which all have demonstrated some efficacy. As minimally invasive procedures flourish, we explore the feasibility of highly selective transoral submandibular neurectomy (TOSN) for the management of sialorrhea.
Methods:
Ten human cadaver dissections of the floor of mouth were performed bilaterally, for a total of 20 separate cases. An intraoral technique for highly selective, submandibular ganglion neurectomy is demonstrated.
Results:
A transoral submandibular ganglion neurectomy was performed in 10 cadavers (20 neurectomies) easily and reliably, without injury to the submandibular duct or the main trunk of the lingual nerve.
Conclusion:
Transoral submandibular neurectomy is an attractive addition to the armamentarium of surgical options for the treatment of medically intractable sialorrhea. Further study in selected patients would need to be performed to demonstrate clinical feasibility.
