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Updated: Apr 20, 2026

Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy
Published on: November 29, 2017
Advancing technologies for the diagnosis and management of infections
Daithi S Heffernan1, Elizabeth D Fox2
1Division of Trauma and Surgical Critical Care, Department of Surgery, Alpert Medical School Brown University, Rhode Island Hospital, 435 APC Building, 593 Eddy Street, Providence, RI 02903, USA.
Abstract:
Infections remain a significant problem among surgical patients. Technological advances, especially in the arena of nano-technology, have markedly improved the ability to detect, prevent and treat surgical infections. No longer limited to culture-based methods of pathogen detection or standard antimicrobial therapies, options for management of surgical infections are rapidly expanding. Such advances are critical in this era of rapidly developing resistant and virulent strains of organisms. Further, our understanding of the host pathogen interaction grows exponentially with the development of computer-based modeling, aiding in expediting research endeavors.
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