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Updated: Apr 20, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
Diffusion tensor imaging for brain malformations: does it help?
Thierry A G M Huisman1, Thangamadhan Bosemani1, Andrea Poretti1
1Section of Pediatric Neuroradiology, Russell H. Morgan Department of Radiology and Radiological Science, Charlotte R. Bloomberg Children's Center, The Johns Hopkins University School of Medicine, Sheikh Zayed Tower, Room 4174, 1800 Orleans Street, Baltimore, MD 21287-0842, USA.
Abstract:
In this article, the basics of diffusion-weighted imaging/diffusion tensor imaging (DTI) are discussed, including a short historical perspective on the fiber dissection technique, followed by a review of selected brain malformations in which DTI and tractography have contributed to a better understanding of the malformations, and by a clinical case in which DTI showed a disorder of the internal neuroarchitecture that could not be correctly appreciated by conventional anatomic magnetic resonance imaging.
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