[Buckwheat allergy can cause live-threatening anaphylaxia]

Area of Science:

• Food allergy research
• Clinical immunology

Background:

• Globalization and increased commercial food products containing buckwheat have led to a rise in buckwheat allergy cases in Denmark.
• Buckwheat allergy can manifest as severe, life-threatening anaphylactic reactions.
• Awareness among medical professionals is crucial for timely diagnosis and management.

Observation:

• Three patients experiencing anaphylactic reactions attributed to buckwheat allergy are presented.
• The study highlights the clinical presentation of buckwheat allergy.

Findings:

• Specific IgE testing for buckwheat protein 2S albumin (Fag e2) is a reliable diagnostic tool, available internationally.
• The increasing prevalence suggests buckwheat allergy is no longer rare in Denmark.

Implications:

• Heightened clinical suspicion for buckwheat allergy is warranted in Denmark.
• Availability of serological tests facilitates accurate diagnosis.
• Further research may be needed to understand the evolving epidemiology of food allergies.