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[HIV-positive newborns via maternal-fetal transmission. Early ophthalmic lesions]
Ophtalmologie : Organe De La Societe Francaise D'Ophtalmologie
|January 1, 1989
Insights
Early-onset serious eye conditions, including ophthalmic zoster and cytomegalovirus retinitis, were observed in infants with human immunodeficiency virus (HIV) infection acquired through maternal-fetal transmission.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Pediatrics
Background:
- Human immunodeficiency virus (HIV) infection in infants can result from maternal-fetal transmission.
- Ophthalmic complications in pediatric HIV are a significant concern, requiring early detection and management.
Observation:
- A cohort of twenty infants diagnosed with HIV infection was monitored since January 1986.
- Two infants presented with severe and early-onset ocular pathologies.
Findings:
- One infant developed ophthalmic zoster (shingles) at three months of age.
- Another infant was diagnosed with cytomegalovirus (CMV) retinitis at six months of age.
- These cases highlight the potential for aggressive ophthalmic manifestations in vertically infected infants.
Implications:
- The findings underscore the importance of regular ophthalmic screening in infants with vertically acquired HIV.
- Early identification of these serious eye lesions is crucial for timely intervention and potentially preserving vision.
- Further research into the specific mechanisms driving these precocious ophthalmic complications in pediatric HIV is warranted.
Abstract:
Since January 1986, the authors have examined twenty infant HIV positives. In two cases specially, some serious and precocious ophthalmic lesions have been found : an ophthalmic zona appeared at the age of three months, a cytomegalovirus retinitis diagnosed at the age of six months. From this series, the particularities of the HIV infection by maternal-fetal transmission are discussed.