Related Experiment Video
Updated: Apr 17, 2026

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
Epidemiology and etiology of non-hodgkin lymphoma
1Department of Public Health Sciences, University of Chicago, 5841 South Maryland Avenue, MC 2000, Chicago, IL, 60637, USA, bchiu@uchicago.edu.
Abstract:
Non-Hodgkin lymphoma (NHL) consists of many histologically and biologically distinct lymphoid malignancies with poorly understood, but possibly distinct, etiologies. The patterns of incidence and time trend vary not only by age, sex, and race/ethnicity in the USA, but also show significant geographic differences, suggesting the potential role of infectious agents, environmental factors, and lifestyle factors in addition to host genetic status in the development of NHL. Important pathogenetic mechanisms include immune modulation and chronic antigen stimulation. Epidemiologic studies in the past two decades have provided intriguing new insights on the possible causes of lymphoma and support the idea that there is some mechanistic commonality of lymphomagenesis, but significant etiologic heterogeneity clearly exists. This review presents a summary of the current understanding of the descriptive epidemiology and etiology of NHL and suggests areas of focus for future epidemiologic research.
More Related Videos
Related Concept Videos
Causality in Epidemiology
Cancer Prevention
Some...
Non-LTR Retrotransposons
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Mechanisms of Retrovirus-induced Cancers
Introduction to Epidemiology

