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Updated: Apr 17, 2026
04:53
A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
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Randomized controlled trials: planning, monitoring, and execution
Elizabeth Hatfield1, Elizabeth Dicks, Patrick S Parfrey
1Clinical Epidemiology, Faculty of Medicine, Memorial University of Newfoundland, Room 3M102A 300 Prince Phillip Drive Health Sciences Centre, St. John's, NL, Canada, A1B 3V6.
Methods in Molecular Biology (Clifton, N.J.)
|February 20, 2015
Summary
Planning and funding large clinical research studies requires robust governance and financial management. This guide details efficient strategies for managing multidisciplinary teams and ensuring successful research execution.
Area of Science:
- Clinical Research
- Research Management
- Team Science
Background:
- Large integrated multidisciplinary teams are crucial for driving innovation in clinical research.
- Effective planning, budgeting, and funding are essential for the success of these complex studies.
Purpose of the Study:
- To provide a comprehensive guide on planning, budgeting, and funding large-scale clinical research studies.
- To outline strategies for executing studies with strong governance and monitoring protocols.
- To detail the management of large, dispersed multidisciplinary research teams.
Main Methods:
- Identifying diverse funding sources for large clinical research projects.
- Developing detailed budgets with clear justifications and reporting requirements.
- Establishing robust financial governance and accountability frameworks.
- Creating and managing multidisciplinary teams for research implementation.
Main Results:
- The chapter outlines a structured approach to financial planning and management for large clinical studies.
- It details the establishment of effective governance and monitoring systems.
- Guidance is provided on building and leading cohesive, dispersed research teams.
Conclusions:
- Successful execution of large clinical research relies on meticulous planning, sound financial oversight, and effective team management.
- Implementing strong governance and monitoring protocols ensures efficient study progression and accountability.
- This chapter serves as a practical resource for researchers managing complex, multidisciplinary projects.
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