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Clinical-oriented Three-dimensional Gait Analysis Method for Evaluating Gait Disorder
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Gait patterns in COPD: the Rotterdam Study.

Lies Lahousse1, Vincentius J A Verlinden2, Jos N van der Geest3

  • 1Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium Dept of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands These authors contributed equally.

The European Respiratory Journal
|February 21, 2015
PubMed
Summary
This summary is machine-generated.

Patients with chronic obstructive pulmonary disease (COPD) have impaired gait rhythm, particularly those who fall. This gait rhythm decline is linked to disease severity and exacerbations.

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Area of Science:

  • Gerontology
  • Pulmonology
  • Biomechanics

Background:

  • Gait disturbances in chronic obstructive pulmonary disease (COPD) can lead to disability and falls.
  • Research on gait kinematics in COPD patients is limited.

Purpose of the Study:

  • To investigate the association between COPD and various gait domains.
  • To explore the link between COPD, gait, and falling.

Main Methods:

  • Gait was assessed using an electronic walkway in the prospective, population-based Rotterdam Study (n=1094, age ≥55 years).
  • Gait was summarized into seven domains: Rhythm, Variability, Phases, Pace, Tandem, Turning, and Base of Support.
  • COPD status was determined, and associations with gait domains were analyzed, adjusting for covariates.

Main Results:

  • COPD patients (n=196) exhibited significantly worse gait Rhythm compared to individuals with normal lung function (n=898).
  • Worse Rhythm was more pronounced in COPD patients with severe airflow limitation, dyspnea, and frequent exacerbations (GOLD group D).
  • Lower forced expiratory volume in 1 second (FEV1) correlated with poorer Rhythm and Pace (cadence and gait velocity).
  • COPD patients who experienced falls had significantly worse Rhythm than non-fallers with COPD.

Conclusions:

  • Individuals with COPD demonstrate impaired gait Rhythm, especially those who fall.
  • The severity of gait Rhythm deterioration in COPD is associated with airflow limitation, symptoms, and exacerbation frequency.