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Consideration of evidence for therapeutic interventions in bovine polioencephalomalacia
1Department of Clinical Sciences, Kansas State University College of Veterinary Medicine, 1800 Denison Avenue, Manhattan, KS 66506, USA.
The Veterinary Clinics of North America. Food Animal Practice
|February 24, 2015
Abstract:
Randomized, masked, prospective clinical trial evidence for therapeutic intervention in naturally occurring bovine polioencephalomalacia (polio) is nonexistent. This article evaluates the use of thiamine and anti-inflammatories in the therapy of polioencephalomalacia based on available information related to the pathophysiology of the disease, induced models, disease outcome in other species (sheep), and parallels in similar disease in humans.

