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Updated: Apr 15, 2026
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
Comparative bone tissue integration of nanostructured and microroughened dental implants
Laëtitia Salou1, Alain Hoornaert, Julien Stanovici
1Inserm U957, Lab. Pathophysiology of Bone Resorption, Faculty of Medicine, University of Nantes, France.
Aim:
The aim was to compare osteointegration of nanostructured implants to a microsurface widely used for titanium dental implants.
Materials & Methods:
Commercial titanium dental implants with smooth or microroughened surfaces were nanostructured. Implants were inserted into the femoral condyles of rabbits. After 2 and 4 weeks, histomorphometry calculation was performed.
Results:
Nanotubes measuring 60 nm in diameter were observed on both S-NANO (roughness: 0.05 μm) and R-NANO (roughness: 0.40 μm) surfaces. The MICRO surface exhibited typical random cavities (roughness: 2.09 μm). At 4 weeks, bone-to-implant contact values were significantly higher for the R-NANO than for the MICRO surface while no differences were observed at 2 weeks.
Conclusion:
Overall, this study shows that the nanostructured surfaces improved osteointegration similar or higher than the MICRO.
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