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Magnesium and Dialysis: The Neglected Cation.
Mohamad Alhosaini1, David J Leehey1
1Loyola University Medical Center, Maywood, IL; Veterans Affairs Hospital, Hines, IL.
Summary
Magnesium imbalances are common in dialysis patients but often overlooked. Regular monitoring and adjusting dialysate magnesium can help maintain normal levels and improve patient outcomes.
Area of Science:
- Nephrology
- Clinical Biochemistry
Background:
- Magnesium homeostasis disorders are prevalent in dialysis patients, yet research attention remains limited.
- Understanding magnesium balance, flux, and clinical significance in this population is crucial.
Observation:
- Plasma magnesium levels are influenced by diet, nutritional status, medications (e.g., proton pump inhibitors), and dialysis prescription.
- Hypomagnesemia and hypermagnesemia are common findings in patients undergoing dialysis.
Findings:
- The review synthesizes current knowledge on magnesium measurement, balance, and factors affecting magnesium levels during dialysis.
- It highlights the prevalence and potential clinical impact of magnesium dysregulation in dialysis patients.
Implications:
- Further interventional studies are needed to establish the clinical benefits of normalizing plasma magnesium.
- Regular predialysis plasma magnesium monitoring and tailored dialysate magnesium adjustments are recommended for optimal patient management.
Keywords:
Gibbs-Donnan effectMagnesiumdialysishemodialysishypermagnesemiahypomagnesemiaperitoneal dialysisproton pump inhibitorsreviewMore Related Videos
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