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Optical coherence tomography in Susac's syndrome
Jacqueline T Bernard1, Rebecca Romero2, Khushboo Agrawal3
1Department of Neurology, University of Chicago Medical Center (UCMC), USA.
Multiple Sclerosis and Related Disorders
|April 17, 2015
Summary
Optical coherence tomography (OCT) aids in diagnosing Susac's syndrome by revealing retinal nerve fiber layer thinning. This non-invasive imaging helps differentiate Susac's syndrome from multiple sclerosis.
Area of Science:
- Neuro-ophthalmology
- Autoimmune diseases
- Diagnostic imaging
Background:
- Susac's syndrome is a rare autoimmune condition affecting the brain, retina, and cochlea.
- Optical coherence tomography (OCT) is a valuable non-invasive imaging technique for neurological and retinal diseases.
Purpose of the Study:
- To demonstrate the utility of OCT in diagnosing Susac's syndrome.
- To differentiate Susac's syndrome from multiple sclerosis (MS) using OCT findings.
Main Methods:
- Case report of 3 patients with Susac's syndrome.
- Analysis of OCT findings at different disease stages.
- Correlation of OCT results with visual field studies.
Main Results:
- OCT revealed patchy thinning of the retinal nerve fiber layer (RNFL), predominantly in nasal quadrants.
- Loss of normal foveal contour was observed, distinguishing it from MS.
- OCT abnormalities correlated with disease severity and visual field deficits.
Conclusions:
- OCT is a useful diagnostic tool for Susac's syndrome.
- OCT can help differentiate Susac's syndrome from MS.
- OCT offers a non-invasive alternative for monitoring disease progression.
Keywords:
BRAOBranch retinal artery occlusionMultiple sclerosisOCTOptical coherence tomographySusac's syndromeMore Related Videos
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