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Related Experiment Video

Updated: Apr 12, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Published on: April 19, 2022

Primary hepatic lymphoma: A case report.

Trupti S Patel¹, Rujuta Malvania¹, Majal C Shah¹

¹Department of Pathology, MP Shah Cancer Hospital, Gujarat Cancer and Research Institute, Ahmadabad, Gujarat, India.

Journal of Cytology

|May 8, 2015

Summary

Primary hepatic lymphoma (PHL) is a rare liver cancer. This case report highlights PHL diagnosis in a patient with a liver mass and normal AFP, emphasizing fine needle aspiration cytology.

Keywords:

Cytology liver non-Hodgkin lymphoma primary hepatic lymphoma

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Last Updated: Apr 12, 2026

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Published on: April 19, 2022

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Area of Science:

Hepatology
Oncology
Pathology

Background:

Primary non-Hodgkin lymphoma (NHL) of the liver is exceptionally rare.
Differentiating liver malignancies from other space-occupying lesions can be challenging.

Observation:

A 60-year-old male presented with abdominal pain and a palpable mass.
Imaging revealed an ill-defined liver mass with calcifications.
The patient exhibited altered liver function but normal alpha-fetoprotein (AFP), hemogram, and bone marrow biopsy.

Findings:

Diagnosis of primary hepatic lymphoma (PHL) was confirmed via cytology and immunohistochemistry.
The case presented unique features including negative viral serology and normal lactate dehydrogenase (LDH).

Implications:

PHL should be considered in the differential diagnosis of liver space-occupying lesions, especially with normal AFP levels.
Fine needle aspiration cytology offers a rapid and safe diagnostic approach for suspected PHL.