Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

775
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
775
Positron Emission Tomography01:29

Positron Emission Tomography

8.1K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
8.1K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

661
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
661

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spinal cord FDG PET uptake in healthy adults: an AI-driven segmentation study.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026
Same author

Quantification of Costal Cartilage Calcification Using <sup>18</sup>F-NaF-PET/CT.

Journal of imaging·2026
Same author

<sup>18</sup>F-NaF and <sup>18</sup>F-FDG PET/CT imaging of spinal instrumentation: case report and review of the literature.

American journal of nuclear medicine and molecular imaging·2026
Same author

Evaluation of physiological bone metabolic activity in the spine with 18F-fluorodeoxyglucose and 18F-sodium fluoride PET: associations with degenerative risk factors.

Nuclear medicine communications·2026
Same author

Determinants of intracranial microcalcification assessed by 18 F-sodium fluoride PET.

Nuclear medicine communications·2026
Same author

<sup>18</sup>F-NaF PET/CT for early detection of osteoporosis in the lumbar spine: two case reports.

American journal of nuclear medicine and molecular imaging·2025
Same journal

Future Directions for [18F]FDG PET in Central Nervous System Diseases.

PET clinics·2026
Same journal

How Fluorine-18-labeled Fluorodeoxyglucose PET Changed Clinical Practice in Central Nervous System Disorders.

PET clinics·2026
Same journal

<sup>18</sup>F-fluorodeoxyglucose PET in Major Psychiatric Disorders.

PET clinics·2026
Same journal

Five Decades of [18F]Fluorodeoxyglucose-PET in Neuropsychiatric Disorders: From Brain Metabolism to Precision Functional Imaging.

PET clinics·2026
Same journal

Brain [18F]FDG PET in Subjective Cognitive Complaints: From Diagnostic Gap to Neurobiological Insight.

PET clinics·2026
Same journal

FDG PET in Movement Disorders and Parkinsonian Syndromes.

PET clinics·2026
See all related articles

Related Experiment Video

Updated: Apr 11, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

20.0K

The Basic Principles of FDG-PET/CT Imaging.

Sandip Basu1, Søren Hess2, Poul-Erik Nielsen Braad2

  • 1Radiation Medicine Center, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, Jerbai Wadia Road, Parel, Mumbai 400012, India.

PET Clinics
|June 9, 2015
PubMed
Summary
This summary is machine-generated.

Positron emission tomography (PET) with 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG) is key to molecular imaging. This review covers essential aspects for successful FDG-PET scans, from physics to patient preparation and interpretation.

Keywords:
FDGFluorodeoxyglucoseHistoryInstrumentationPET/CTPhysicsPositron emission tomography/computed tomographyRadiochemistry

More Related Videos

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.8K
A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
08:55

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice

Published on: April 17, 2019

19.3K

Related Experiment Videos

Last Updated: Apr 11, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

20.0K
Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.8K
A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
08:55

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice

Published on: April 17, 2019

19.3K

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiochemistry

Background:

  • Positron emission tomography (PET) using 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG) is a cornerstone of molecular imaging.
  • FDG-PET imaging necessitates extensive interdisciplinary collaboration among diverse specialists.

Purpose of the Study:

  • To provide a concise overview of fundamental considerations for successful FDG-PET patient examinations.
  • To highlight key areas including physics, instrumentation, radiochemistry, biology, patient preparation, and interpretation.

Main Methods:

  • Review of essential components for FDG-PET imaging.
  • Discussion of basic physics and instrumentation.
  • Exploration of radiochemistry and molecular/cell biology principles.
  • Guidance on patient preparation and normal tracer distribution.
  • Identification of potential interpretive pitfalls.

Main Results:

  • Successful FDG-PET imaging relies on understanding basic physics and instrumentation.
  • Radiochemistry and molecular/cell biology are crucial for tracer development and application.
  • Proper patient preparation and knowledge of normal tracer distribution are vital for accurate interpretation.
  • Awareness of potential interpretive pitfalls enhances diagnostic reliability.

Conclusions:

  • Effective FDG-PET imaging requires a comprehensive understanding of its multidisciplinary components.
  • Interdisciplinary collaboration is paramount for optimizing patient examinations and diagnostic accuracy.
  • This review serves as a foundational guide for professionals involved in FDG-PET imaging.