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Glutathione.

Amer M Alanazi1, Gamal A E Mostafa1, Abdullah A Al-Badr1

  • 1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Profiles of Drug Substances, Excipients, and Related Methodology
|June 9, 2015
PubMed
Summary
This summary is machine-generated.

Glutathione, a key antioxidant peptide, is comprehensively profiled, detailing its synthesis, physical properties, and diverse analytical methods. This profile aids researchers in understanding and utilizing glutathione effectively.

Keywords:
BiosynthesisDescriptionGlutathioneMethods of analysisPhysical characteristicsReviewsSpectral propertiesStabilitySynthesisUses

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Area of Science:

  • Biochemistry
  • Analytical Chemistry

Background:

  • Glutathione is a vital endogenous peptide with significant antioxidant and metabolic roles.
  • Understanding its properties is crucial for various biological and pharmaceutical applications.

Purpose of the Study:

  • To provide a comprehensive profile of glutathione.
  • To detail its nomenclature, synthesis, physical characteristics, and analytical methodologies.

Main Methods:

  • Synthesis and biosynthesis pathways.
  • Physical characterization (solubility, X-ray diffraction, crystal structure, thermal analysis).
  • Spectroscopic and various other analytical techniques (NMR, MS, chromatography, electrochemistry).

Main Results:

  • Detailed physical and chemical properties of glutathione.
  • A wide array of analytical methods for identification and quantification.
  • Information on stability and existing reviews.

Conclusions:

  • This profile serves as a valuable resource for glutathione research.
  • It consolidates essential information on glutathione's properties and analysis.