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Prasugrel Hydrochloride
Mahmoud M H Al Omari1, Nidal A Qinna2, Iyad S Rashid1
1The Jordanian Pharmaceutical Manufacturing Co., Naor, Jordan.
Summary
This review details prasugrel hydrochloride (HCl), a crucial antiplatelet medication. It covers synthesis, properties, and applications, offering a comprehensive resource for researchers and clinicians.
Area of Science:
- Pharmacology and Medicinal Chemistry
- Chemical Synthesis and Analysis
Background:
- Prasugrel hydrochloride (HCl) is a significant antiplatelet agent used in cardiovascular medicine.
- Existing literature provides fragmented information on its comprehensive profile.
Purpose of the Study:
- To compile a detailed profile of prasugrel HCl.
- To consolidate information on its chemical properties, synthesis, and applications.
Main Methods:
- Literature review encompassing 158 references.
- Compilation of data on nomenclature, formulae, elemental analysis, and physical properties.
- Discussion of preparation methods, analytical techniques, stability, and pharmacology.
Main Results:
- A comprehensive description of prasugrel HCl, including its chemical and physical characteristics.
- Detailed methods for the preparation of prasugrel HCl, its intermediates, and derivatives.
- An overview of analytical methods, stability, applications, and pharmacological actions.
Conclusions:
- This profile serves as a centralized resource for prasugrel HCl.
- It provides essential information for researchers, formulators, and clinicians working with prasugrel HCl.
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