Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phase I Oxidative Reactions: Overview01:19

Phase I Oxidative Reactions: Overview

1.0K
Phase I biotransformation, or functionalization, is a crucial chemical process that converts drugs and other xenobiotics into more water-soluble forms, facilitating expulsion from the body. It involves oxidative, reductive, and hydrolytic reactions that add or unveil polar functional groups on lipophilic substrates. Key players in phase I reactions are the mixed-function oxidases. Situated in liver cell microsomes, these enzymes predominantly carry out drug metabolism. They require molecular...
1.0K
Phase I Reactions: Oxidation of Carbon-Heteroatom and Miscellaneous Systems01:15

Phase I Reactions: Oxidation of Carbon-Heteroatom and Miscellaneous Systems

551
Oxidative reactions are pivotal in metabolizing numerous compounds, including pharmaceutical drugs. These reactions often occur in carbon-heteroatom systems, such as carbon-nitrogen, carbon-sulfur, and carbon-oxygen.
In carbon-nitrogen systems, aliphatic and aromatic amines can undergo oxidative reactions. Secondary and tertiary amines, like those found in tricyclic antidepressants, can undergo N-dealkylation, a process that involves the oxidation of the alkyl group. In addition, oxidative...
551
Redox Reactions01:24

Redox Reactions

59.4K
Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
59.4K
Redox Reactions01:27

Redox Reactions

1.4K
Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
1.4K
Redox Equilibria: Overview01:23

Redox Equilibria: Overview

1.7K
A reduction-oxidation reaction is commonly called a redox reaction. In a redox reaction, electrons are transferred from one species to another rather than being shared between or among atoms. The reducing agent or reductant is the species that loses electrons and gets oxidized in the process. The species that gains electrons and gets reduced in the process is the oxidizing agent or oxidant. Redox reactions are represented as two separate equations called half-reactions, where one equation...
1.7K
Oxidation of Alcohols02:37

Oxidation of Alcohols

18.3K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
18.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pd/Ti<sub>3</sub>C<sub>2</sub> nanohybrids as heterogeneous catalyst for efficient catalytic reduction of hazardous water pollutants at ambient conditions.

Scientific reports·2026
Same author

Occurrence and characterization of microplastics in dry pet food: Investigating geographical variations between European and South American markets.

Environmental pollution (Barking, Essex : 1987)·2026
Same author

Late-Stage Aryl NCF<sub>3</sub> and SCF<sub>3</sub> Installation Enabled by Coupling Flow-Generated Anions with Aryl Thianthrenium Salts.

Journal of the American Chemical Society·2026
Same author

Direct δ-Lactone Synthesis From Free Alcohols via Photoinduced δ-C(sp<sup>3</sup>)-H Carbonylation in Flow.

Angewandte Chemie (International ed. in English)·2026
Same author

Synthesis of Stable Pyrrole-Fused Diazacyclic Allenes.

The Journal of organic chemistry·2026
Same author

Photoorganocatalytic trifluoromethylation of (het)arenes in green conditions.

Beilstein journal of organic chemistry·2026
Same journal

Fluorescent merocyanines: from fundamental properties to applications as molecular probes, in bioimaging and as emissive dye aggregates.

Chemical Society reviews·2026
Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026
Same journal

Catalytic valorization of polyolefins: from catalysts and processes to reactors.

Chemical Society reviews·2026
Same journal

Designing stable π-radicals.

Chemical Society reviews·2026
Same journal

Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules.

Chemical Society reviews·2026
Same journal

Selective carbon-carbon bond cleavage involving alkene moieties.

Chemical Society reviews·2026
See all related articles

Related Experiment Video

Updated: Apr 6, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
07:06

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Published on: November 15, 2017

12.2K

Liquid phase oxidation chemistry in continuous-flow microreactors.

Hannes P L Gemoets1, Yuanhai Su1, Minjing Shang1

  • 1Department of Chemical Engineering and Chemistry, Micro Flow Chemistry & Process Technology, Eindhoven University of Technology, Den Dolech 2, 5612 AZ Eindhoven, The Netherlands. t.noel@tue.nl.

Chemical Society Reviews
|July 24, 2015
PubMed
Summary
This summary is machine-generated.

Continuous-flow microreactors offer superior heat and mass transfer for liquid phase oxidation reactions. This review covers the technology, chemistry, and scale-up potential of these advanced reactors.

More Related Videos

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations
13:09

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations

Published on: January 4, 2018

39.8K
A Continuous-flow Photocatalytic Reactor for the Precisely Controlled Deposition of Metallic Nanoparticles
11:49

A Continuous-flow Photocatalytic Reactor for the Precisely Controlled Deposition of Metallic Nanoparticles

Published on: April 10, 2019

10.4K

Related Experiment Videos

Last Updated: Apr 6, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
07:06

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Published on: November 15, 2017

12.2K
Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations
13:09

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations

Published on: January 4, 2018

39.8K
A Continuous-flow Photocatalytic Reactor for the Precisely Controlled Deposition of Metallic Nanoparticles
11:49

A Continuous-flow Photocatalytic Reactor for the Precisely Controlled Deposition of Metallic Nanoparticles

Published on: April 10, 2019

10.4K

Area of Science:

  • Chemical Engineering
  • Organic Chemistry
  • Process Chemistry

Background:

  • Microreactors offer enhanced heat and mass transfer, improving safety and efficiency in chemical reactions.
  • Continuous-flow chemistry in microreactors is gaining attention for its potential in liquid phase oxidation.
  • Traditional batch processes often face challenges with heat management and safety when using hazardous oxidants.

Purpose of the Study:

  • To provide an up-to-date overview of liquid phase oxidation chemistry in continuous-flow microreactors.
  • To discuss both the technological and chemical aspects of this reaction methodology.
  • To highlight the safety advantages and scale-up potential of microreactor technology.

Main Methods:

  • Review of existing literature on continuous-flow microreactor technology for oxidation reactions.
  • Analysis of mass and heat transfer phenomena within microreactors.
  • Discussion of various oxidants (oxygen, hydrogen peroxide, ozone) used in flow chemistry.

Main Results:

  • Microreactors provide significantly enhanced heat and mass transfer compared to conventional reactors.
  • Continuous-flow systems enable safer handling of hazardous oxidants.
  • High interfacial areas in microreactors facilitate efficient reactions.
  • Demonstrated potential for scalability of continuous-flow oxidation processes.

Conclusions:

  • Continuous-flow microreactors represent a promising technology for efficient and safe liquid phase oxidation.
  • Fundamental principles of heat and mass transfer are crucial for reactor selection and optimization.
  • The technology offers significant advantages for both laboratory research and industrial scale-up.