Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

9.9K
9.9K
DNA as a Genetic Template02:05

DNA as a Genetic Template

28.9K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
28.9K
DNA Isolation01:34

DNA Isolation

203.1K
DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.
203.1K
DNA Isolation01:24

DNA Isolation

46.9K
DNA isolation protocols can be fast and straightforward or complex and time-consuming depending on the type and quality of DNA required for further processing. For example, plasmid DNA extraction is a bit more complicated than genomic DNA extraction because of the need for an appropriate lysis method to separate plasmid DNA from gDNA during isolation. However, for specific applications, such as long-range DNA sequencing that require a good yield of high- quality DNA samples, we need to follow...
46.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

KIR2DL4-HLAG interaction at human NK cell-oligodendrocyte interfaces regulates IFN-γ-mediated effects.

Molecular immunology·2018
Same author

Y-Short Tandem Repeat Multiplex Systems - Y-PLEX™ 6 and Y-PLEX™ 5.

Forensic science review·2015
Same author

Extraction of DNA from Forensic Biological Samples for Genotyping.

Forensic science review·2015
Same author

Extraction of DNA from Human Remains.

Forensic science review·2015
Same author

Assessment of DNA Extracted from Forensic Samples Prior to Genotyping.

Forensic science review·2015
Same author

Principles, Practice, and Evolution of Capillary Electrophoresis as a Tool for Forensic DNA Analysis.

Forensic science review·2015

Related Experiment Video

Updated: Apr 5, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

16.8K

Training of Forensic DNA Scientists - A Commentary.

M Turnbough1, A Eisenberg2, L L Shade3

  • 1Forensic and Investigative Genetics, University of North Texas Health Center, Fort Worth, TX, USA. Meredith.Turnbough@unthsc.edu.

Forensic Science Review
|August 6, 2015
PubMed
Summary

Forensic DNA analysis is crucial for criminal investigations but faces backlogs due to increasing sample volumes and limited analyst training. Dedicated training facilities are essential for high-throughput DNA profiling and consistent results.

Keywords:
AutomationDNA databaseSTRforensic DNA analysisforensic laboratorytrainingworkflow integration

More Related Videos

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

23.6K
DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA

Published on: July 15, 2011

27.9K

Related Experiment Videos

Last Updated: Apr 5, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

16.8K
Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

23.6K
DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA

Published on: July 15, 2011

27.9K

Area of Science:

  • Forensic Science
  • Molecular Biology
  • Criminal Justice

Background:

  • Forensic DNA analysis has significantly advanced criminal investigations over the past 20 years.
  • Increasing sample volumes from crime scenes and databases strain forensic DNA laboratory capacity, leading to significant backlogs.
  • Limited resources for training new analysts pose a major challenge to timely sample processing and maintaining quality standards.

Purpose of the Study:

  • To address the challenges of increasing sample backlogs in forensic DNA laboratories.
  • To highlight the critical role of comprehensive training for forensic DNA analysts.
  • To discuss the importance of specialized training facilities for high-throughput DNA profiling.

Main Methods:

  • The article reviews current challenges in forensic DNA sample processing and backlog management.
  • It examines the necessity of high-quality training aligned with established quality assurance standards (e.g., FBI, INTERPOL).
  • The discussion includes the benefits of dedicated training facilities for automated sample processing.

Main Results:

  • High-throughput forensic DNA laboratories require efficient sample processing to manage growing backlogs.
  • Effective analyst training is paramount for ensuring consistent, high-quality DNA profiling results.
  • Dedicated training programs accelerate the development of skilled personnel for forensic DNA analysis.

Conclusions:

  • Addressing forensic DNA backlogs necessitates investment in robust analyst training programs.
  • Specialized training facilities can enhance laboratory efficiency and throughput.
  • Standardized, high-quality training is fundamental to the integrity and value of forensic DNA analysis in criminal justice.