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Symptomatic Surgically Treated Non-neoplastic Cysts of the Central Nervous System: A Clinicopathological Study From
Nasir Ud Din1, Huma Arshad1, Zubair Ahmad1
1Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi.
Objective:
To report clinicopathologic features of symptomatic surgically removed non-neoplastic cysts of the central nervous system (CNS).
Study Design:
Case series.
Place And Duration Of Study:
The Aga Khan University Hospital, Karachi, from 2003 to 2012.
Methodology:
All non-neoplastic CNS cysts reported during the study period were retrieved and reviewed. Age, gender, location, histologic type and clinical features were noted.
Results:
A total of 124 cysts were diagnosed in the study period. These included 44 epidermoid cysts (mean age 30.5 ± 13.8 years), 35 colloid cysts (mean age 31 ±13.2 years), 32 arachnoid cysts (mean age 24.8 ±20.2 years), 6 dermoid cysts, 3 enterogenous cysts and Rathke's cleft cysts each and 1 ependymal cyst. All cyst types mainly presented in young adults in both genders with signs and symptoms of a mass lesion.
Conclusion:
Non-neoplastic cyst mainly presented like a CNS mass lesion in young adults. Epidermoids were the most common type of these cysts in the present series followed by the colloid and the arachnoid cysts.