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Related Concept Videos

Collagens are the Major Structural Proteins of ECM01:13

Collagens are the Major Structural Proteins of ECM

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Three main types of fibers are secreted by fibroblasts: collagen fibers, elastic fibers, and reticular fibers. Collagen fiber is made from fibrous protein subunits linked together to form a long, straight fiber. Collagen fibers, while flexible, have great tensile strength, resist stretching, and give ligaments and tendons their characteristic resilience and strength. These fibers hold connective tissues together, even during the body's movement.
Connective tissue proper includes loose...
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Fibril-associated Collagen01:11

Fibril-associated Collagen

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Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
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Type IV Collagen of Basal Lamina01:05

Type IV Collagen of Basal Lamina

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Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen  forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
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Cell-matrix's Response to Mechanical Forces01:13

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In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
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Structural Protein Function01:56

Structural Protein Function

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Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
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Fibrous Proteins00:55

Fibrous Proteins

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Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...
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In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen
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In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

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Structured Mechanical Collage.

Zhe Huang, Jiang Wang, Hongbo Fu

    IEEE Transactions on Visualization and Computer Graphics
    |September 11, 2015
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a new method for creating visually appealing 3D mechanical collages using artist designs and graphic principles. User studies confirm these structured collages are more aesthetically pleasing than prior approaches.

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    Area of Science:

    • Computer Graphics
    • Computational Design
    • Artificial Intelligence

    Background:

    • Automated generation of complex 3D structures remains a challenge.
    • Integrating artistic principles into computational design requires novel approaches.

    Purpose of the Study:

    • To develop a method for constructing 3D structured mechanical collages from a database of elements.
    • To guide the construction process using established graphic design principles: unity, variety, and contrast.

    Main Methods:

    • Utilizing artist-designed proxy models to guide the assembly of numerous database elements.
    • Implementing algorithms that adhere to principles of unity, variety, and contrast for aesthetic coherence.

    Main Results:

    • The proposed method successfully generates 3D mechanical collages with enhanced visual appeal.
    • A user study validated that the generated collages are perceived as more visually pleasing compared to existing methods.

    Conclusions:

    • The integration of graphic design principles significantly improves the aesthetic quality of automatically generated 3D collages.
    • This work advances the field of computational creativity and automated design by producing visually superior results.