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Presentations and Outcome of Thyroiditis from a Tertiary Care Hospital of Karachi
Saeed Ahmed Mahar1, Muhammad Shahid1, Aqiba Sarfaraz1
1Department of Endocrinology, Liaquat National Hospital and Medical College, Karachi.
Insights
Fever and sore throat are common symptoms of thyroiditis. Most patients recover fully, but some may develop hypothyroidism, highlighting the need for appropriate management.
Area of Science:
- Endocrinology
- Internal Medicine
Background:
- Thyroiditis presents with diverse clinical manifestations.
- Understanding short-term outcomes is crucial for patient management.
Purpose of the Study:
- To evaluate clinical presentations of thyroiditis.
- To assess short-term outcomes in thyroiditis patients.
- To analyze thyroid function tests and inflammatory markers.
Main Methods:
- A case series design was employed.
- Data collected from 26 thyroiditis patients (June 2014-Feb 2015).
- Included adults (18-70 years) with acute thyroiditis; excluded pregnant/psychiatric/chronically ill patients.
Main Results:
- Fever (65.4%) and sore throat (69.2%) were primary symptoms.
- Elevated Erythrocyte Sedimentation Rate (ESR) observed in all patients.
- 88.5% showed suppressed Thyroid Stimulating Hormone (TSH) and 57.7% had elevated Free T4 (FT4).
Conclusions:
- Fever and sore throat are key indicators of thyroiditis.
- All patients had elevated ESR, indicating inflammation.
- Most patients achieved full recovery, though some developed hypothyroidism.
Objective:
To assess the clinical presentations and short-term outcomes of patients with thyroiditis presenting to a tertiary care hospital in Karachi, Pakistan.
Study Design:
Case series.
Place And Duration Of Study:
Department of Endocrinology, Liaquat National Hospital, Karachi, from June 2014 to February 2015.
Methodology:
Patients between 18 and 70 years of age with acute onset of thyroiditis confirmed on thyroid scan or clinical judgment presenting to the outpatient services were included in the study. Pregnant females, psychiatric patients and patients having other chronic illnesses were excluded from the study.
Results:
A total of 26 patients with thyroiditis attended the endocrine clinic. Mean age of patients was 41.2 ± 11.12 years. There were 18 (69.2%) females. Clinical presentations were fever (65.4%), tender neck (23.1%), goiter (19.2%), localized tenderness in neck and palpable lymph nodes (26.9%). Major symptoms reported were: sore throat (69.2%), weight loss (38.5%), upper respiratory tract infection, thyroid pain, tremor, sweating and fever of unknown origin in 26.9% cases. All the patients had raised Erythrocyte Sedimentation Rate (ESR). Low Thyroid Stimulating Hormone (TSH) < 0.4 mlU/L was seen in 88.5% and 57.7% had raised Free T4 > 1.8 ng/dL. Complete recovery was seen in 88.5% patients while 11.5% had early hypothyroidism.
Conclusion:
Fever and sore throat were the main presenting features of thyroiditis patients. ESR was raised in all patients. A majority of patients had complete recovery with appropriate management; however, few cases developed hypothyroidism.