Related Experiment Video
Updated: Apr 1, 2026
07:23
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
8.8K
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EARLY TYPE 3 NEOVASCULARIZATION
Alexandra Miere1, Giuseppe Querques, Oudy Semoun
1Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université Paris EstCréteil, France.
Retina (Philadelphia, Pa.)
|October 13, 2015
Summary
Optical coherence tomography angiography reveals a distinct high-flow, tuft-shaped network in outer retinal proliferations associated with Type 3 neovascularization in age-related macular degeneration.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Exudative age-related macular degeneration (AMD) can lead to Type 3 neovascularization.
- Understanding the imaging characteristics of this condition is crucial for diagnosis and management.
Observation:
- This study analyzed optical coherence tomography angiography (OCTA) features in treatment-naive patients with early-stage Type 3 neovascularization.
- Conventional angiography and spectral domain optical coherence tomography were used for correlation.
Findings:
- OCTA consistently demonstrated a tuft-shaped, high-flow anastomosis originating from the deep capillary plexus in the outer retina.
- These lesions extended into the subretinal pigment epithelium space.
- A small, clue-like lesion in the choriocapillaris was observed in most cases, occasionally connected to the choroid.
Implications:
- OCTA provides detailed visualization of Type 3 neovascularization in exudative AMD.
- The characteristic findings on OCTA can aid in early and accurate diagnosis.
- Further research may explore therapeutic strategies targeting these specific vascular abnormalities.
Related Concept Videos
01:19Imaging Studies VII: Vascular Imaging
474
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
474
01:27Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
520
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
520
01:28Imaging Studies for Cardiovascular System V: CT
567
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
567
01:28Angle Closure Glaucoma: Treatment
1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
669
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
669