Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

6.5K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.5K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.9K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.9K
iPS Cell Differentiation01:22

iPS Cell Differentiation

3.3K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.3K
Embryonic Stem Cells00:58

Embryonic Stem Cells

33.4K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
33.4K
Embryonic Stem Cells00:57

Embryonic Stem Cells

5.9K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
5.9K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.6K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial - Brothers in arms: regenerative biology and dentistry.

European cells & materials·2022
Same author

Bioengineered tooth emulation systems for regenerative and pharmacological purposes.

European cells & materials·2021
Same author

The effects of ageing on dental pulp stem cells, the tooth longevity elixir.

European cells & materials·2019
Same author

Use of supercharged cover screw as static magnetic field generator for bone healing, 2nd part: in vivo enhancement of bone regeneration in rabbits.

Journal of biological regulators and homeostatic agents·2017
Same author

The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro.

European cells & materials·2017
Same author

Use of supercharged cover screw as static magnetic field generator for bone healing, 1st part: in vitro enhancement of osteoblast-like cell differentiation.

Journal of biological regulators and homeostatic agents·2017
Same journal

INTERVERTEBRAL DISC DEGENERATION INSTIGATES VERTEBRAL ENDPLATE REMODELING AND FACET JOINT PATHOLOGY IN A LARGE ANIMAL MODEL.

European cells & materials·2025
Same journal

BURN-SYNOVECTOMY MOUSE MODEL FOR TEMPOROMANDIBULAR JOINT OSTEOARTHRITIS.

European cells & materials·2025
Same journal

DESIGNER FAT CELLS: ADIPOGENIC DIFFERENTIATION OF CRISPR-CAS9 GENOME-ENGINEERED INDUCED PLURIPOTENT STEM CELLS.

European cells & materials·2025
Same journal

Development of a 3D-printed bioabsorbable composite scaffold with mechanical properties suitable for treating large, load-bearingarticular cartilage defects.

European cells & materials·2023
Same journal

Understanding the effects of mesenchymal stromal cell therapy for treating osteoarthritis using an in vitro co-culture model.

European cells & materials·2023
Same journal

Disrupting mechanical homeostasis promotes matrix metalloproteinase-13 mediated processing of neuron glial antigen 2 in mandibular condylar cartilage.

European cells & materials·2023
See all related articles

Related Experiment Video

Updated: Mar 30, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.5K

Stem cell-based approaches in dentistry.

T A Mitsiadis1, G Orsini, L Jimenez-Rojo

  • 1University of Zurich, Faculty of Medicine, Orofacial Development and Regeneration, Institute of Oral Biology, ZZM, Plattenstrasse 11, 8032 Zurich, Switzerland.thimios.mitsiadis@zzm.uzh.ch.

European Cells & Materials
|November 13, 2015
PubMed
Summary
This summary is machine-generated.

Stem cell therapies offer promising alternatives for dental regeneration, addressing limitations of traditional treatments. Research focuses on optimizing stem cell use, scaffolds, and whole-tooth regeneration for improved dental outcomes.

More Related Videos

Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
07:56

Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells

Published on: November 16, 2018

7.3K
Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

3.1K

Related Experiment Videos

Last Updated: Mar 30, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.5K
Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
07:56

Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells

Published on: November 16, 2018

7.3K
Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

3.1K

Area of Science:

  • Regenerative Dentistry
  • Biomaterials Science
  • Stem Cell Biology

Background:

  • Dental pulp and periodontal lesion repair presents significant clinical challenges.
  • Current restorative dentistry relies on materials with uncertain efficacy and longevity.
  • Stem cell-based therapies offer potential for improved structural and functional dental outcomes.

Purpose of the Study:

  • To review current restorative dental techniques and stem cell research.
  • To explore the translation of stem cell research into clinical dental practice.
  • To identify challenges and emerging strategies in dental tissue regeneration.

Main Methods:

  • Review of existing literature on dental restorative techniques.
  • Analysis of in vivo studies on dental mesenchymal stem cells in animal models.
  • Examination of bioactive scaffolds and pluripotent stem cell applications.

Main Results:

  • Dental mesenchymal stem cells show potential for pulp and periodontal regeneration.
  • Key challenges include stem cell homogeneity, quality control, delivery, and tissue integration.
  • Bioactive scaffolds and stem/induced pluripotent cells offer novel regenerative strategies.

Conclusions:

  • Stem cell therapies, bioactive scaffolds, and whole-tooth regeneration are promising for dentistry.
  • Further research is needed to overcome challenges in stem cell application and tissue integration.
  • Translating basic stem cell research into clinical practice is crucial for advancing dental treatments.