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Panic disorder.

¹Psychopharmacology Program, Ohio State University College of Medicine, Columbus.

American Family Physician

|June 1, 1989

Summary

This summary is machine-generated.

Panic disorder impacts 1.4% of people, often co-occurring with major depressive disorder. Effective treatments include antidepressants and behavioral interventions for panic disorder and agoraphobia.

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Area of Science:

Psychiatry
Clinical Psychology

Background:

Panic disorder affects 1.4% of the general population.
Comorbidity with major depressive disorder is high, affecting nearly 70% of patients.
Agoraphobia frequently develops secondary to panic disorder, impacting management.

Purpose of the Study:

To review the epidemiology and treatment of panic disorder.
To highlight the significant comorbidity with major depressive disorder.
To discuss pharmacological and behavioral treatment options.

Main Methods:

Literature review of panic disorder, major depressive disorder, and treatment modalities.
Synthesis of information on epidemiological data, comorbidity rates, and therapeutic efficacy.
Analysis of treatment responses to antidepressants, monoamine oxidase inhibitors, and alprazolam.

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Main Results:

Panic disorder has a notable prevalence in the general population.
A significant percentage of panic disorder patients experience major depressive disorder.
Pharmacological treatments like tricyclic antidepressants, monoamine oxidase inhibitors, and alprazolam show efficacy.
Behavioral interventions are crucial for managing associated agoraphobia.

Conclusions:

Panic disorder and major depressive disorder share significant overlap and require integrated management.
A combination of pharmacotherapy and behavioral therapy offers a comprehensive approach to treating panic disorder and its sequelae.
Understanding comorbidity and associated conditions like agoraphobia is key to effective patient care.