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Effect of a Strict 'No-Talking' Policy During Intravitreal Injection on Post-Injection Endophthalmitis
Background And Objective:
To report the effect of a "no-talking" policy during intravitreal injection (IVI) on post-injection endophthalmitis.
Patients And Methods:
Retrospective, comparative, consecutive case series of patients receiving IVI between Jan. 1, 2009, and Dec. 31, 2012. A 24-month "usual care" period was compared to a 24-month no-talking period, during which a strategy to further minimize speech during IVI was implemented.
Results:
During the usual care period, 47,155 IVIs were performed, with nine culture-positive cases (0.019%), including seven due to oral pathogens (0.015%). During the no-talking period, 82,658 IVIs were performed, with eight culture-positive cases (0.010%), including two due to oral pathogens (0.002%). The no-talking policy was associated with a decreased endophthalmitis risk (P = .004), including oral pathogen-associated endophthalmitis (P = .02).
Conclusion:
This study demonstrates that a more stringent no-talking policy during IVI may reduce the risk of post-injection endophthalmitis.
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