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Related Concept Videos

Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

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Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
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Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
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Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

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Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
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Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Tracheostomy Suctioning II: Procedure01:23

Tracheostomy Suctioning II: Procedure

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Tracheostomy suctioning is a vital nursing procedure that involves removing secretions from the tracheostomy tube to maintain airway patency and prevent respiratory complications. Nurses need to understand the proper technique for tracheostomy suctioning to ensure patient safety and comfort. In this guide, we will outline the step-by-step process for performing tracheostomy suctioning, including preparing the sterile field, donning personal protective equipment (PPE), lubricating and connecting...
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Tracheostomy Suctioning I: Pre-Procedural Steps01:26

Tracheostomy Suctioning I: Pre-Procedural Steps

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Tracheostomy suctioning is a critical procedure healthcare professionals perform to maintain a patent airway in patients with a tracheostomy tube. This procedure is necessary when secretions accumulate in the airway, causing respiratory distress. Here is a step-wise procedural guide for performing tracheostomy suctioning using an open system.
Equipment Required
First, gather all necessary equipment: a sterile suction catheter, a sterile disposable container, sterile gloves, a towel or...
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Pneumothorax-I01:26

Pneumothorax-I

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A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
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Related Experiment Video

Updated: Mar 29, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
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Thoracoscopic Lung Suffusion.

Todd L Demmy1

  • 1Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.

Thoracic Surgery Clinics
|November 28, 2015
PubMed
Summary

A new lung suffusion technique allows regional delivery of agents for metastatic disease. This thoracoscopic method offers a less invasive approach to treating lung malignancies.

Area of Science:

  • Pulmonary Medicine
  • Surgical Oncology
  • Medical Technology

Background:

  • The lung is a frequent site for metastatic cancer, often representing the sole measurable malignancy.
  • Previous regional lung therapies faced limitations due to invasiveness and organ fragility, hindering widespread adoption.

Purpose of the Study:

  • To introduce and describe a novel thoracoscopic vascular control technique for lung permeation with therapeutic agents, termed lung suffusion.
  • To present preclinical data supporting the efficacy and safety of lung suffusion.
  • To report early human clinical experience with this innovative regional lung therapy.

Main Methods:

  • Development of a thoracoscopic approach for vascular control within the lung.
  • Administration of therapeutic agents via permeation of lung tissue using the suffusion technique.
Keywords:
Isolated lung perfusionLung cancerMinimally invasive surgeryPulmonary suffusionRegional chemotherapy

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  • Preclinical evaluation in animal models and early-phase human trials.

    • Main Results:

    • Successful demonstration of lung permeation with agents using the suffusion technique in preclinical studies.
    • Early human experience indicates feasibility and potential for this minimally invasive regional therapy.
    • Lung suffusion offers a distinct method compared to prior regional lung treatment strategies.

    Conclusions:

    • Lung suffusion represents a promising, less invasive method for regional therapy of lung metastases.
    • This technique addresses limitations of previous approaches by enabling controlled agent delivery.
    • Further clinical investigation is warranted to establish the full therapeutic potential of lung suffusion.