Taking nanomedicine teaching into practice with atomic force microscopy and force spectroscopy.

Area of Science:

• Nanomedicine
• Biophysics
• Medical Education

Background:

• Atomic Force Microscopy (AFM) is a critical tool for studying molecular interactions in nanomedicine.
• Integrating advanced techniques like AFM into medical and bioscience curricula is essential for future research and clinical applications.
• Nanomedicine holds significant promise for disease diagnosis and treatment.

Purpose of the Study:

• To develop and evaluate a practical, hands-on Atomic Force Microscopy (AFM) course for graduate biosciences and medical students.
• To provide students with direct experience in utilizing AFM for biological sample analysis.
• To foster student engagement with nanomedicine applications.

Main Methods:

• Implementation of a two-session practical course focused on AFM.
• Students performed AFM scanning of human blood cells.
• Students conducted force spectroscopy measurements of fibrinogen-platelet interactions.

Main Results:

• The hands-on AFM course received an average student rating of 4.7 out of 5.
• Students demonstrated enthusiasm and produced high-quality AFM images and force spectroscopy data.
• The course successfully introduced students to AFM applications in nanomedicine.

Conclusions:

• The hands-on AFM course was a successful educational initiative, providing valuable practical experience.
• Exposure to AFM enhances students' understanding of molecular interactions at the nanoscale, crucial for nanomedicine.
• Incorporating nanomedicine and AFM training into medical and bioscience curricula is vital for future healthcare advancements.