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Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases

Hans Helmut Niller1, Ferenc Banati2, Daniel Salamon3

  • 1Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.

Advances in Experimental Medicine and Biology
|December 15, 2015
PubMed
Summary

Epstein-Barr virus (EBV) infection causes significant epigenetic changes in both viral and host cell genomes. These viral-induced epigenetic alterations contribute to distinct cellular epigenotypes and disease development, particularly in cancers like Burkitt lymphoma and nasopharyngeal carcinoma.

Keywords:
Epigenetic signatureGenome-wide demethylationHeterochromatic histone marksHost cell methylomeViral epigenotypes

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