Related Experiment Video
Updated: Mar 28, 2026

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
Published on: June 26, 2020
Porphyrin-modified DNA as Construction Material in Supramolecular Chemistry and Nano-architectonics
1School of Chemistry & Institute for Life Sciences University of Southampton Highfield, Southampton, SO17 1BJ, UK. est@soton.ac.uk.
Abstract:
An overview is given on the developments of using porphyrin-modified DNA for the construction of functional assemblies. Strategies for the synthesis and characterisation are presented alongside selected applications where the porphyrin modification has proven to be particularly useful, but also revealed its limitations. We also discuss implications on property and behaviour of the porphyrin-DNA, where similar issues could arise using other hydrophobic and bulky substituents on DNA.

