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Updated: Mar 27, 2026

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Dissection Techniques and Histological Sampling of the Heart in Large Animal Models for Cardiovascular Diseases
Published on: June 16, 2022
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Heart
M Colvin1,2, J M Smith2,3, M A Skeans2
1Department of Cardiology, University of Michigan, Ann Arbor, MI.
Summary
Heart transplant numbers are rising steadily for both adults and children, with more candidates added to waiting lists each year. Despite increased procedures, long-term survival rates for pediatric heart transplant recipients show ongoing challenges.
Area of Science:
- Cardiology
- Transplantation Medicine
- Public Health
Background:
- The demand for heart transplants is increasing globally.
- Rising numbers of candidates on heart transplant waiting lists present significant challenges.
- Steady annual increases in heart transplant procedures offer hope.
Purpose of the Study:
- To analyze trends in heart transplant waitlist activity for adult and pediatric candidates.
- To evaluate the volume and outcomes of heart transplant procedures over time.
- To assess survival rates for pediatric heart transplant recipients.
Main Methods:
- Analysis of national heart transplant waitlist data.
- Review of heart transplant procedure statistics from 2003 to 2014.
- Examination of survival data for pediatric heart transplant recipients (2008-2012).
Main Results:
- Heart transplants increased by 28.4% from 2003 to 2014, with 2679 procedures in 2014.
- Both adult and pediatric waiting lists saw increased additions and removals due to transplant.
- Pediatric heart transplants rose to 410 in 2014; 5-year survival was 81.7% for transplants in 2008-2012.
Conclusions:
- While heart transplant volume is increasing, waitlist demand continues to grow.
- Improved outcomes and survival rates are crucial, especially for pediatric recipients.
- Continued monitoring and research are essential to address the gap between demand and supply in heart transplantation.
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