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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
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Unplanned Resection of Sarcoma
Nicholas S Tedesco1, Robert M Henshaw
1From Medstar Washington Hospital Center, Medstar Orthopedic Institute, Georgetown University School of Medicine, Washington, DC.
The Journal of the American Academy of Orthopaedic Surgeons
|January 14, 2016
Summary
Unplanned sarcoma resections lead to worse surgical outcomes and increased morbidity, often requiring repeat surgeries. Adhering to oncologic principles is crucial for optimal sarcoma management and patient prognosis.
Area of Science:
- Orthopaedic Oncology
- Surgical Pathology
Background:
- Sarcomas are rare and often misdiagnosed as benign lesions.
- Unplanned resections occur when surgeons lack awareness or adherence to oncologic principles.
Purpose of the Study:
- To highlight the negative consequences of unplanned sarcoma resections.
- To emphasize the importance of proper surgical management in orthopaedic oncology.
Main Methods:
- Review of studies on oncologic and surgical outcomes after unplanned resections.
- Analysis of factors contributing to poor surgical outcomes and increased morbidity.
Main Results:
- Unplanned resections result in mixed oncologic outcomes but significantly worse surgical outcomes.
- Failure to adhere to oncologic principles increases morbidity and amputation rates.
- No current diagnostic modality accurately predicts residual disease after unplanned resection.
Conclusions:
- Repeat surgery is often necessary, increasing costs and patient morbidity.
- Medical malpractice litigation is common in cases of delayed diagnosis and unnecessary amputations following unplanned sarcoma resections.
