Impact of Oxygenation Status on 18F-FDG Uptake in Solid Tumors
Marie-Aline Neveu1, Vanesa Bol2, Anne Bol2
1Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.
Advances in Experimental Medicine and Biology
|January 20, 2016
Abstract:
The influence of changes in tumor oxygenation (monitored by EPR oximetry) on the uptake of 18F-FDG tracer was evaluated using micro-PET in two different human tumor models. The 18F-FDG uptake was higher in hypoxic tumors compared to tumors that present a pO2 value larger than 10 mmHg.


