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3D Navigo™ versus TRUS-guided prostate biopsy in prostate cancer detection.
Maudy Gayet1,2, Anouk van der Aa3,4, Peter Schmitz3
1Department of Urology, Jeroen Bosch Hospital, Post office box 90153, 5200 ME, 's-Hertogenbosch, The Netherlands. M.Gayet@jbz.nl.
World Journal of Urology
|February 6, 2016
Summary
The Navigo™ system, a 3D transrectal ultrasound (TRUS) technology, did not improve prostate cancer detection rates compared to conventional 2D TRUS in biopsy-naive men. This study found no added value for the Navigo™ system in detecting prostate cancer (PCa).
Area of Science:
- Urology
- Medical Imaging
- Oncology
Background:
- Transrectal ultrasound (TRUS)-guided biopsies are limited in prostate cancer (PCa) detection.
- New imaging technologies are being explored to enhance PCa detection accuracy.
- The Navigo™ system utilizes TRUS images and electrospatial monitoring for 3D prostate modeling.
Purpose of the Study:
- To compare the cancer detection rates of the Navigo™ system versus conventional TRUS.
- To evaluate the efficacy of 3D TRUS in patients without a prior history of PCa.
Main Methods:
- Retrospective study of 325 patients undergoing 12-core prostate biopsies.
- Data collected from September 2013 to February 2015 at Jeroen Bosch Hospital.
- Comparison of PCa detection rates between the Navigo™ system (77.8% of sessions) and conventional TRUS.
Main Results:
- No statistically significant difference in PCa detection rates between Navigo™ (39.9%) and conventional TRUS (46.2%).
- The Navigo™ system was not associated with detecting PCa, clinically significant PCa, or in subgroup analyses.
- Study limitations include retrospective design and differing numbers of biopsy sessions and physician experience.
Conclusions:
- The Navigo™ system, a 3D TRUS technology, offers no added value over conventional 2D TRUS for PCa detection.
- This finding applies to both biopsy-naive men and those with prior negative biopsies.
- Further research may be needed to explore advanced imaging in prostate biopsy guidance.
