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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Towards a molecular-genetic analysis of mammalian development

J Rossant, A L Joyner

    Trends in Genetics : TIG
    |August 1, 1989
    PubMed

    Abstract:

    The mouse has been a slower starter than many other organisms in the race to unravel the genetic control of embryonic development. Recent cloning of putative developmental genes combined with new approaches to manipulating the mouse genome seem set, however, to allow the mammalian embryo to move towards the front of the field.

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