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Updated: Mar 24, 2026

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Published on: August 15, 2025
Complicated Giant Pilomatrixoma of the Parotid Region
Sedat Aydın1, Zekiye Eda Bilmez1, Suleyman Erdogdu1
1ENT Department, Dr. Lutfi Kirdar Kartal Education and Research Hospital, İstasyon Caddesi Merdivenli Sokak No 5 D 6, Kartal, 34860 Istanbul, Turkey.
Objective:
Pilomatrixoma (calcifying epithelioma of Malherbe) is a benign soft tissue tumour arising from dermis or subcutaneous tissue which should be considered in differential diagnosis of preauricular lesions especially when skin fixation is present.
Case Report:
Twenty-three year old male referred to our clinic with complaint of left preauricular swelling over 18 months which enlarged and became painful in the last 2 months. Because the lesion showed signs of infection, surgery was planned after medical therapy was completed. FNAB suggest pleomorphic adenoma as preliminary diagnosis. US or MRI showed no specific feature.
Treatment And Prognosis:
Total excision, superficial parotidectomy with facial nerve sparing was performed after regression of infectious signs. Postoperatively no recurrence was detected.
Conclusion:
Pilomatrixomas are benign tumours but have diagnostic difficulties according to clinical and cytologic findings. This rare lesion should be kept in mind to avoid misdiagnosis as malign parotid tumours, particularly in the presence of skin change.
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